As the Guide explains, you hold the spray with your thumb on the bottom and your first and middle fingers on either side of the device. (See below.) Then, you gently insert the nozzle into one nostril until your fingers on either side of the nozzle are against the bottom of the person’s nose.

How do you administer naloxone prefilled syringe?

As the Guide explains, you hold the spray with your thumb on the bottom and your first and middle fingers on either side of the device. (See below.) Then, you gently insert the nozzle into one nostril until your fingers on either side of the nozzle are against the bottom of the person’s nose.

How much naloxone do you administer?

Adults and children—At first, 2 or 4 milligrams (mg) (1 spray into one nostril). Another spray may be given into the other nostril every 2 to 3 minutes until the patient responds or until emergency medical assistance becomes available.

Can naloxone be self administered?

Naloxone is usually not self-administered. Tell others about the possible need to use naloxone, how to use it, and where it’s kept in case of overdose.

What are common administration routes for naloxone buccal?

Naloxone is absorbed not only through intravenous (IV), but also by intramuscular (IM), subcutaneous (SC), endotracheal, sublingual, intralingual, submental, and nasal routes.

Can naltrexone be self-administered?

Currently available formulations of both buprenorphine/naloxone and methadone require daily supervised administration early in treatment or daily self-administration once the patient is clinically stable.

Which routes would be most appropriate to administer the naloxone?

Intramuscular naloxone works more quickly than intranasal administration of the same dose; however, there may be advantages to intranasal administration. The opioid antagonist naloxone can reverse the life-threatening effects of opioid overdose when given intravenously, intramuscularly, or intranasally.

What is the least preferred route of administration for naloxone?

Naloxone can be given endotracheally, but such use is supported by only one published anecdotal care report and should be considered the least desirable route of administration, probably requiring higher doses than other routes.

Can naloxone be administered buccal?

Naloxone is the standard treatment in response to cases of suspected opiate overdose. Buccal formulation of naloxone is a novel alternative to the licensed naloxone injection which, by removing the risk of accidental needle-stick, may be safer and easier to administer.

How often can you administer naloxone?

Narcan can be given every 2 to 3 minutes until the person wakes up and breathes normally. There is no maximum dose of Narcan, which means you can give as many doses as needed.